• Franny Hulscher, Yousra Farouki, Benjamin Mine, Thomas Bonnet, Maud Wang, Stephanie Elens, SuarezJuan VazquezJVDepartment of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium., Lise Jodaitis, Noémie Ligot, Gilles Naeije, Boris Lubicz, and Adrien Guenego.
• Department of Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.
• World Neurosurg. 2022 Apr 1; 160: e566-e572.

ObjectiveGood clinical outcome predictors have been emphasized in mechanical thrombectomy (MT) for acute ischemic stroke (AIS) with large vessel occlusion. MT for distal, medium vessel occlusions (DMVO) is still debated. We sought to assess the factors associated with clinical outcome after MT for DMVO.MethodsWe retrospectively analyzed the data of consecutive patients who underwent MT for a primary DMVO in 1 large academic center and aimed to identify the baseline clinical, imaging, and MT factors associated with good clinical outcome (defined as modified Rankin scale score of 0-2) at 3 months.ResultsBetween January 2018 and January 2021, 61 patients underwent a MT for an AIS with a primary DMVO. Overall, good clinical outcome was achieved in 56% (34 of 61) of our patients. In multivariate analysis, an older age (odds ratio [OR] 0.89 [95% confidence interval 0.83-0.96], P = 0.003), longer puncture to recanalization time (OR 0.97 [0.93-0.99], P = 0.033), and higher baseline core volume (OR 0.84 [0.75-0.94], P = 0.003) decreased the probability of good clinical outcomes, while a final complete (or near-) recanalization (modified Thrombolysis In Cerebral Infarction [mTICI] score 2c-3) increased the probability of good outcome (OR 14.19 [1.99-101.4], P = 0.008).ConclusionsAn older age, a longer puncture to recanalization time, and a higher baseline core volume decreased the probability of good clinical outcomes, while successful recanalization (mTICI 2c-3) was associated with better outcomes after MT for DMVO.Copyright © 2022 Elsevier Inc. All rights reserved.

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