• Derege Kebede, Chris Zielinski, Peter Ebongue Mbondji, Issa Sanou, Wenceslas Kouvividila, and Paul-Samson Lusamba-Dikassa.
• World Health Organization Regional Office for Africa, PO Box 6, Brazzaville, Congo kebeded@who.int.
• J R Soc Med. 2014 May 1; 107 (1 suppl): 77-84.

ObjectiveTo estimate the sources of funds for health research (revenue) and the uses of these funds (expenditure).DesignA structured questionnaire was used to solicit financial information from health research institutions.SettingForty-two sub-Saharan African countries.ParticipantsKey informants in 847 health research institutions in the 42 sub-Saharan African countries.Main Outcome MeasuresExpenditure on health research by institutions, funders and subject areas.ResultsAn estimated total of US$ 302 million was spent on health research by institutions that responded to the survey in the World Health Organization (WHO) African Region for the biennium 2005-2006. The most notable funders for health research activities were external funding, ministries of health, other government ministries, own funds and non-profit institutions. Most types of health research performers spent significant portions of their resources on in-house research, with medical schools spending 82% and government agencies 62%. Hospitals spent 38% of their resources on management, and other institutions (universities, firms, etc.) spent 87% of their resources on capital investment. Research on human immunodeficiency virus/tuberculosis and malaria accounted for 30% of funds, followed by research on other communicable diseases and maternal, perinatal and nutritional conditions (23%).ConclusionsResearch on major health problems of the Region, such as communicable diseases, accounts for most of the research expenditures. However, the total expenditure is very low compared with other WHO regions.© The Royal Society of Medicine.

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