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- P J Hutchinson, A Gimson, P G Al-Rawi, M T O'Connell, M Czosnyka, and D K Menon.
- Academic Department of Neurosurgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. pjah2@cam.ac.uk
- Neurocrit Care. 2006 Jan 1; 5 (3): 202-5.
IntroductionFulminant hepatic encephalopathy has a high mortality.MethodsThis case report describes the role of cerebral microdialysis as an adjunct to the management of a 49 - year-old woman with hepatic encephalopathy secondary to a paracetamol overdose.ResultsThe application of the microdialysis technique, by detecting a very low cerebral glucose concentration in the presence of a normal plasma glucose, assisted in clinical decision making.ConclusionsCerebral microdialysis, by enabling continuous on-line monitoring of substrate delivery and metabolism, may have a role in the management of patients with fulminant hepatic failure.
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