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Case Reports
Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection.
- Tomoaki Yamasaki, Yuhei Sakata, Takehisa Suekane, and Hiroko Nebiki.
- Department of Gastroenterology, Osaka City General Hospital, Japan.
- Intern. Med. 2022 Aug 15; 61 (16): 2457-2461.
AbstractAlthough dexmedetomidine (DEX) is a widely used analgesic and sedative agent for endoscopic procedures, cardiovascular complications, such as bradycardia and hypotension, are frequently experienced. We herein report the first case of asystole-induced bradycardia due to DEX during endoscopic submucosal dissection (ESD). An 81-year-old man without cardiovascular diseases was referred for gastric carcinoma. ESD was started after administering a loading dose of DEX followed by a continuous maintenance infusion of DEX. The patient's heart rate gradually decreased, and then cardiac arrest occurred. DEX has a risk of cardiac arrest, so bradycardia should not be underestimated during sedation with DEX.
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