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- Takanori Suzuki, Itaru Naitoh, Takahito Katano, Kentaro Matsuura, Yoshihito Nagura, Kei Fujiwara, Shunsuke Nojiri, and Hiromi Kataoka.
- Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan.
- Intern. Med. 2022 Aug 15; 61 (16): 2471-2475.
AbstractThe case of a 28-year-old man who had primary sclerosing cholangitis and autoimmune hepatitis overlapping syndrome (PSC-AIH OS) complicated by ulcerative colitis (UC) is reported. First, he was diagnosed with PSC complicated by UC and initially treated with ursodeoxycholic acid and mesalazine. Twenty-four months later, liver damage reappeared, and we performed a liver biopsy, which showed the features of AIH. We eventually diagnosed him with PSC-AIH OS complicated by UC. If liver damage worsens in PSC patients, PSC-AIH OS should be considered. The optimum management approach for PSC-AIH OS should be established.
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