• Daniel Munblit, Timothy R Nicholson, Dale M Needham, Nina Seylanova, Callum Parr, Jessica Chen, Alisa Kokorina, Louise Sigfrid, Danilo Buonsenso, Shinjini Bhatnagar, Ramachandran Thiruvengadam, Ann M Parker, Jacobus Preller, Sergey Avdeev, Frederikus A Klok, Allison Tong, Janet V Diaz, GrooteWouter DeWNCD Department, Rehabilitation Programme, WHO, Geneva, Switzerland., Nicoline Schiess, Athena Akrami, Frances Simpson, Piero Olliaro, Christian Apfelbacher, Regis Goulart Rosa, Jennifer R Chevinsky, Sharon Saydah, Jochen Schmitt, Alla Guekht, Sarah L Gorst, Jon Genuneit, Luis Felipe Reyes, Alan Asmanov, Margaret E O'Hara, Janet T Scott, Melina Michelen, Charitini Stavropoulou, John O Warner, Margaret Herridge, and Paula R Williamson.
• Department of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia. daniel.munblit08@imperial.ac.uk.
• Bmc Med. 2022 Feb 4; 20 (1): 5050.

BackgroundA substantial portion of people with COVID-19 subsequently experience lasting symptoms including fatigue, shortness of breath, and neurological complaints such as cognitive dysfunction many months after acute infection. Emerging evidence suggests that this condition, commonly referred to as long COVID but also known as post-acute sequelae of SARS-CoV-2 infection (PASC) or post-COVID-19 condition, could become a significant global health burden.Main TextWhile the number of studies investigating the post-COVID-19 condition is increasing, there is no agreement on how this new disease should be defined and diagnosed in clinical practice and what relevant outcomes to measure. There is an urgent need to optimise and standardise outcome measures for this important patient group both for clinical services and for research and to allow comparing and pooling of data.ConclusionsA Core Outcome Set for post-COVID-19 condition should be developed in the shortest time frame possible, for improvement in data quality, harmonisation, and comparability between different geographical locations. We call for a global initiative, involving all relevant partners, including, but not limited to, healthcare professionals, researchers, methodologists, patients, and caregivers. We urge coordinated actions aiming to develop a Core Outcome Set (COS) for post-COVID-19 condition in both the adult and paediatric populations.© 2022. The Author(s).

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