• Internal medicine · Sep 2022

    Case Reports

    Clopidogrel-induced Eosinophilia with Hypercalcemia: A Case Report.

    • Kazuhiro Yamada, Kazuhisa Asai, Misaki Yanagimoto, Risa Sone, Satsuki Inazu, Ryo Mizutani, Hideaki Kadotani, Tetsuya Watanabe, Yoshihiro Tochino, and Tomoya Kawaguchi.
    • Department of Respiratory Medicine, Osaka Metropolitan University Graduate School of Medicine, Japan.
    • Intern. Med. 2022 Sep 1; 61 (17): 2681-2685.

    AbstractThere are few cases describing the association of eosinophilia with hypercalcemia, and drug-induced eosinophilia with hypercalcemia has not been reported. A 74-year-old man had been diagnosed with asthma 4 months earlier. He was admitted due to eosinophilia with hypercalcemia. Chest computed tomography showed a nodule in the left lung and mediastinal lymphadenopathy. By obtaining a detailed medical history, clopidogrel was suspected as the prime cause of eosinophilia. After the discontinuation of clopidogrel, the eosinophilia with hypercalcemia, lung nodule and mediastinal lymphadenopathy improved. Clopidogrel-induced eosinophilia can potentially cause hypercalcemia. Obtaining a detailed clinical history is important in diagnosing the cause of eosinophilia.

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