• Internal medicine · Sep 2022

    Case Reports

    Cryptogenic Fibrosing Pleuritis with Rapidly Progressive Restrictive Ventilatory Dysfunction.

    • Ayane Torii, Yoshitaka Ono, Shohei Obayashi, Asako Kitahara, Kana Oshinden, Yukihiro Horio, Kyoko Niimi, Naoki Hayama, Tsuyoshi Oguma, Kazuhito Hatanaka, Koichiro Asano, and Yoko Ito.
    • Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Japan.
    • Intern. Med. 2022 Sep 1; 61 (17): 2649-2653.

    AbstractCryptogenic bilateral fibrosing pleuritis is a rare condition, and its pathogenesis and clinical course are poorly understood, with no established therapy available. A 61-year-old man presented with bilateral pleural thickening and lymphocytic exudative effusions. The patient was diagnosed with fibrosing pleuritis with no evidence of a known etiology on a surgical pleural biopsy. Within 16 months from the onset of respiratory symptoms, restrictive ventilatory impairment progressed rapidly, resulting in hypercapnic respiratory failure requiring home oxygen and non-invasive positive pressure ventilation therapies.

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