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- Hiroshi Yamamoto, Masamichi Komatsu, Kei Sonehara, Yuichi Ikuyama, Kazuhisa Urushihata, Kazunari Tateishi, Yoshiaki Kitaguchi, Atsuhito Ushuiki, Shiho Asaka, Takeshi Uehara, Satoshi Kawakami, Kentaro Mori, Kazutoshi Hamanaka, Kenichi Nishie, Akira Hebisawa, and Masayuki Hanaoka.
- First Department of Internal Medicine, Shinshu University School of Medicine, Japan.
- Intern. Med. 2022 Sep 1; 61 (17): 2637-2642.
AbstractA 69-year-old man was diagnosed with immunoglobulin (Ig) G4-related disease (IgG4-RD) at 62 years old. At that time, he had high serum IgG4 levels and bilateral submandibular gland swelling on CT; thus, a gland biopsy was performed. Because a reticular shadow was found on chest CT, a lung surgical biopsy was also performed. The specimens revealed usual interstitial pneumonia (UIP) pattern interstitial pneumonia with some IgG4-positive cells. The patient was subsequently followed up without treatment. His forced vital capacity and radiological findings progressively deteriorated, consistent with UIP pattern interstitial lung disease but different from a lung lesion of IgG4-RD.
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