• Chest · Jul 2022

    Review

    Hematology Emergencies in Critically Ill Adults: Malignant Hematology.

    • Jenna Spring and Laveena Munshi.
    • Interdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada; Sinai Health System and University Health Network, Toronto, ON, Canada.
    • Chest. 2022 Jul 1; 162 (1): 120-131.

    AbstractAs outcomes have improved across the hematologic malignancy population, candidacy for ICU admission has increased. This complex population may develop a variety of complications related to their treatment or underlying disease that can result in critical illness necessitating ICU support. This review highlights common causes of critical illness associated with hematologic malignancies, including the following: (1) neutropenic sepsis; (2) hyperleukocytosis and leukostasis across patients with acute myeloid leukemia; (3) complications of acute promyelocytic leukemia; (4) tumor lysis syndrome; and (5) critical care complications that can arise following hematopoietic stem cell transplantation.Copyright © 2022. Published by Elsevier Inc.

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