• Yuanyuan Ji, Yufeng Wang, Huijuan Lou, Yuxin Zhang, Yangshengjie Liu, Xu Zheng, Xiushuang Jia, Kang Yang, Hongshi Zhang, and Deyu Cong.
• Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, China.
• Medicine (Baltimore). 2022 Feb 11; 101 (6): e28780e28780.

BackgroundLimb spasms are a common complication of stroke. It not only affects the quality of life of stroke survivors, but also brings an economic burden. Tuina combined with physical therapy is widely used in the rehabilitation of poststroke spasticity. However, there is no supporting evidence for its efficacy and safety. This study aimed to evaluate the effectiveness and safety of Tuinas combined with physical therapy in the treatment of spasticity after stroke.MethodsLiterature will be collected from the following databases: China Biology Medicine (CBM), Wanfang Database, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), PubMed, Embase, Cochrane Library, and Web of Science; We will include randomized controlled trials of Tuina combined with physical therapy for poststroke spasticity range from the establishment to May 1, 2021. There were no limitations to the publication time, and the language was limited to Chinese and English. The primary outcome was evaluated using the Modified Ashworth scale, and the secondary outcomes were the simplified Fugl-Meyer Assessment scale, Modified Barthel Index, Functional Independence Measurement (FIM), and Visual Analog Scale. RevMan V.5.4.1 software was used for the meta-analysis. The Cochrane Intervention System Evaluation Manual analyzes the risk of bias, and the recommended grading assessment, development and evaluation are used to assess the quality of evidence.Ethics And DisseminationThis study will be based on published systematic review studies, no ethical approval is required and the results of the study will be published in a peer-reviewed scientific journal.Systematic Review RegistrationINPLASY2021110064.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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