• Clinics · Jan 2022

    Review

    Sudden unexpected death in Parkinson's disease: Insights from clinical practice.

    • Fulvio A Scorza, Marcia Guimarães-Marques, Mariana Nejm, de AlmeidaAntônio Carlos GACGNeuroscience Center of the Woman Health "Professor Geraldo Rodrigues de Lima", Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil; Laboratory of Experimental and Computational, Carla A Scorza, FioriniAna CACNeuroscience Center of the Woman Health "Professor Geraldo Rodrigues de Lima", Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil; Department of Phonoaudiology, Escola Paulista de Medicina (, and Josef Finsterer.
    • Neuroscience Discipline, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil; Neuroscience Center of the Woman Health "Professor Geraldo Rodrigues de Lima", Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil. Electronic address: scorza@unifesp.br.
    • Clinics (Sao Paulo). 2022 Jan 1; 77: 100001.

    AbstractClassified as the second most common neurodegenerative disorder associated with aging after Alzheimer's disease, Parkinson's disease (PD) is the most common movement disorder. In the last decade, despite advances in treatment, mortality rates linked with PD continued to reach significant figures. Available studies have shown that compared with healthy controls, patients with PD are accompanied by high rates of premature death. This is usually caused by factors such as pneumonia and cerebrovascular and cardiovascular diseases. Recently, it has been demonstrated that a significant proportion of patients with PD die suddenly. This is referred to as a sudden and unexpected death in PD (SUDPAR). Here, we focus on the magnitude of SUDPAR. Finally, it is important to learn more about SUDPAR for the implementation of effective prevention strategies.Copyright © 2022 HCFMUSP. Published by Elsevier España, S.L.U. All rights reserved.

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