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- Togo Sakai, Masao Takemoto, Jiro Ueno, Eiji Nyuta, Yoshibumi Antoku, Tokushi Koga, and Takuya Tsuchihashi.
- Cardiovascular Center, Steel Memorial Yawata Hospital, Japan.
- Intern. Med. 2022 Sep 15; 61 (18): 2747-2751.
AbstractA 74-year-old man was admitted to our hospital to undergo radiofrequency catheter ablation (RFCA) of persistent atrial fibrillation (AF). We found that he had a history of heparin-induced thrombocytopenia (HIT). Thus, a direct thrombin inhibitor, Argatroban Hydrate (Argatroban®), was used instead of heparin as anticoagulation therapy during the RFCA procedure. Finally, the AF was successfully treated by RFCA without any complications. Given these findings, the direct thrombin inhibitor Argatroban® may be effective and feasible for anticoagulation therapy during RFCA procedures for AF in patients with HIT, such as the present case.
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