• Wagner Iared, José Eduardo Mourão, Andrea Puchnick, Fernando Soma, and David Carlos Shigueoka.
• Department of Internal Medicine, Universidade Federal de São Paulo, Brazilian Cochrane Centre, São Paulo, Brazil.
• Cochrane Db Syst Rev. 2022 Feb 21; 2 (2): CD008461CD008461.

BackgroundThe subclavian arteries are two major arteries of the upper chest, below the collar bone, which come from the arch of the aorta. Endovascular treatment for stenosis of the subclavian arteries includes angioplasty alone, and with stenting. There is insufficient evidence to guide the use of stents following angioplasty for subclavian artery stenosis. This is the second update of a review first published in 2011.ObjectivesThe aim of this review was to determine whether stenting was more effective than angioplasty alone for stenosis of the subclavian artery.Search MethodsFor this update, the Cochrane Vascular Information Specialist searched the Cochrane Vascular Specialised Register, CENTRAL, MEDLINE, Embase, CINAHL, and LILACS databases, and the World Health Organization International Clinical Trials Registry Platform and ClinicalTrials.gov trials registers to 2 February 2021.Selection CriteriaWe searched for randomised controlled trials of endovascular treatment of subclavian artery lesions that compared angioplasty alone and stent implantation.Data Collection And AnalysisTwo review authors independently evaluated studies to assess eligibility. Discrepancies were resolved by discussion. If there was no agreement, we asked a third review author to assess the study for inclusion. We planned to undertake data collection and analysis in accordance with recommendations described in the Cochrane Handbook for Systematic Reviews of Interventions, and assess the certainty of the evidence using a GRADE approach.Main ResultsTo date, we have not identified any completed or ongoing randomised controlled trials that compare percutaneous transluminal angioplasty and stenting for subclavian artery stenosis.Authors' ConclusionsThere is currently insufficient evidence to determine whether stenting is more effective than angioplasty alone for stenosis of the subclavian artery.Copyright © 2022 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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