• Internal medicine journal · Feb 2022

    Hospitalisation and associated costs of gastrointestinal bleeding from primary prevention aspirin use in South Australia: a retrospective case series analysis.

    • Gregory Roberts, Maxwell Baker, Hannah Leiblich, Maryssa Paulose, Matthew Pegoli, Lucas Panagopoulos, Carly Schiller, and Vijayaprakash Suppiah.
    • SA Pharmacy, Flinders Medical Centre, Adelaide, South Australia, Australia.
    • Intern Med J. 2022 Feb 1; 52 (2): 318-321.

    AbstractWe assessed hospitalisations for gastrointestinal bleeding directly related to primary prevention aspirin in lower risk patients for a 6-month period in three South Australian hospitals. Those with related underlying pathology or concurrent causative medication were excluded. Identified patients (n = 22) carried little co-morbidity, 41% received prior proton-pump inhibitors and 68% were aged >70 years. Mean hospital admission cost was $6769 (95% confidence interval $5198-$8340), with projected state and national annual costs of $0.57 and $8.12 million respectively. In light of recent guideline changes, clinicians need to vigorously assess the need for primary prevention aspirin.© 2022 Royal Australasian College of Physicians.

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