• Panminerva medica · Sep 2022

    Review

    Metabolic syndrome and bladder cancer.

    • Marialaura Righetto, Daniele Modonutti, Francesco G Celso, Vittorio Fulcoli, and Mariangela Mancini.
    • Department of Surgery, Urological Clinic, AULSS 6 Euganea, Camposampiero, Padua, Italy - marialaura.righetto@aulss6.veneto.it.
    • Panminerva Med. 2022 Sep 1; 64 (3): 316-323.

    AbstractMetabolic syndrome (MetS) is a widely diffused dysmetabolism, well known to be associated with an increased cardiovascular risk. However, a growing burden of evidence links MetS with several malignancies, potentially influencing the onset, progression, and therapeutic response. In this work, we critically explored the relationship between MetS and bladder cancer through a narrative review, researching the most recent literature on the topic using PubMed, MEDLINE, and EMBASE. We found that the current evidence on the subject is heterogeneous and inconsistent, making it difficult to draw definitive conclusions. Furthermore, since MetS would be a modifiable oncological risk factor, more high-quality data is needed for tailored treatment of bladder cancer.

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