• Toshihiro Sato, Go Anan, Takuo Hirose, Ryo Tajima, Kento Hoshino, Yuka Miyake, Tsugumi Fukunaga, Toshiko Kato, Akari Endo, Hiroki Ito, Shingo Nakayama, Hideaki Hashimoto, Katsuya Ishiyama, Tomoyoshi Kimura, and Takefumi Mori.
• Division of Nephrology and Endocrinology, Tohoku Medical and Pharmaceutical University, Sendai 983-8536, Japan.
• Medicina (Kaunas). 2022 Feb 18; 58 (2).

AbstractBackground and Objectives: Peritoneal dialysis (PD)-related peritonitis is a critical problem. However, preoperative risk factors for PD-related peritonitis have not been established. Thus, we aimed to determine the preoperative risk factors for PD-related peritonitis. Materials and Methods: This is a single-center prospective observational study. All peritonitis episodes during the study period were recorded, and preoperative and intraoperative clinical parameters were compared between patients with and without peritonitis to examine risk factors for PD-related peritonitis. Furthermore, subcutaneous and abdominal fat volumes were evaluated using computed tomography. Results: Among a total of 118 patients, 24 patients developed peritonitis. The proportion of male patients (83% vs. 61%, p = 0.04), body mass index (25 vs. 22 kg/m2, p = 0.04), and subcutaneous fat area (120 vs. 102 cm2, p = 0.01) were significantly higher and the proportion of patients living with family members (75% vs. 94%, p = 0.02) was significantly lower in the peritonitis group than in the non-peritonitis group. There were no significant differences in age, operation method, surgeon experience, previous abdominal surgery, medical history of diabetic nephropathy, serum albumin level, and renal function between the two groups. Conclusions: Male patients with high subcutaneous fat who are living alone might be at higher risk of PD-related peritonitis. These characteristics might be useful in risk assessment and patient education before PD induction.

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