• Crit Care · Jan 2010

    Comment

    The complex interplay between delirium, sepsis and sedation.

    • John P Kress.
    • Department of Medicine, Section of Pulmonary and Critical Care, University of Chicago, 5841 South Maryland, MC 6026, Chicago, IL 60637, USA. jkress@medicine.bsd.uchicago.edu
    • Crit Care. 2010 Jan 1;14(3):164.

    AbstractCritically ill patients requiring mechanical ventilation frequently suffer from intensive care unit delirium, a syndrome associated with numerous poor measured outcomes. The relationship between delirium, sepsis, and sedation is complex. A discussion of the recent study ('Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS [maximizing efficacy of targeted sedation and reducing neurological dysfunction] randomized controlled trial') by Pandharipande and colleagues is presented in this commentary.

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