• Astha Prasai, Abhishek Pant, Asmita Neupane, Subash Pant, and Sailesh Pradhan.
• Department of Medicine, HAMS Hospital, Dhumbarahi, Kathmandu, Nepal.
• JNMA J Nepal Med Assoc. 2021 Oct 15; 59 (242): 996-999.

IntroductionIncreasing antibiotic resistance has created a global public health threat worldwide. Acinetobacter species is one of the important pathogenic organisms in the hospital setting due to its ability to persist in the hospital environment for long. Its resistance to commonly used antibiotics can prolong hospital stay, increase financial burden, and increase morbidity and mortality. This study aims to find the prevalence of extensive drug resistant Acinetobacter species in the sputum sample of Intensive Care Unit patients admitted in a tertiary care center.MethodsA descriptive cross-sectional study was conducted in a tertiary care center among the hospital records from May 2017 to May 2021, after ethical approval (Reference number: 2104202101). All the Intensive Care Unit patients with isolated acinetobacter species in their sputum samples within the past four years were collected and Statistical Package for Social Sciences version 25 was used for analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.ResultsOf the total 409, 196 (47.9%) (95% Confidence Interval= 43.06-52.74) of Acinetobacter species in the sputum sample had extensive drug resistance. Of these, 193 (98.5%) and 1 (0.5%) of the extensive drug resistant Acinetobacter species were resistant to carbapenem and polymyxin respectively.ConclusionsPrevalence of extensive drug resistant acinetobacter was found higher compared to other studies.

14 keywords...

hide…