• Internal medicine · Oct 2022

    Case Reports

    A Case of Methicillin-resistant Staphylococcus aureus Necrotizing Bronchitis after Radiotherapy in Combination with Axitinib.

    • Hiroki Nakatsumi, Satoshi Watanabe, Kazuki Gohara, Takafumi Kobayashi, Yoshihiro Takeda, Kazuo Kasahara, and Seiji Yano.
    • Department of Respiratory Medicine, Kanazawa University Hospital, Japan.
    • Intern. Med. 2022 Oct 1; 61 (19): 2931-2934.

    AbstractA 38-year-old man with renal cell carcinoma was referred to our hospital because of a productive cough. He had received radiotherapy for lung metastasis and been treated with axitinib. Bronchoscopy revealed necrosis in the bronchi of the right middle and lower lobes. Culture of the necrotic bronchial specimen revealed methicillin-resistant Staphylococcus aureus (MRSA). Although radiotherapy in combination with axitinib carries a risk of causing airway toxicity, MRSA necrotizing bronchitis has not been reported. Physicians should consider the possibility of infectious necrotizing bronchitis if irradiated patients show prolonged respiratory symptoms.

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