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- Hiroyuki Suzuki, Tomoya Sano, Yasumasa Shimasaki, Maki Yamaguchi, Tatsuya Ide, Teruko Arinaga-Hino, Reiichiro Kuwahara, Keisuke Amano, Koichi Oshima, Koji Nagafuji, Hiroaki Ida, Hironori Koga, and Takuji Torimura.
- Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
- Intern. Med. 2022 Oct 1; 61 (19): 2967-2972.
AbstractThrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome is a systemic inflammatory disorder characterized by the above-mentioned symptoms. Because of the similarity in phenotypes between TAFRO syndrome and decompensated liver cirrhosis, an accurate diagnosis is often difficult. We herein report a 62-year-old Japanese patient with TAFRO syndrome who was misdiagnosed with intractable ascites associated with liver cirrhosis. Improvement of symptoms after treatment with prednisolone was associated with interleukin-6 rather than C-reactive protein. The pathogenesis of TAFRO syndrome, which has similar clinical manifestations to liver cirrhosis, remains unclear, and our findings may help elucidate the concept of this condition.
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