• J. Thorac. Cardiovasc. Surg. · Jul 2022

    Outcomes of aortic valve repair in children resulting in bicuspid anatomy: Is there a need for tricuspidization?

    • Antonia Schulz, Edward Buratto, Fraser R O Wallace, Nicholas Fulkoski, Robert G Weintraub, Christian P Brizard, and Igor E Konstantinov.
    • Department of Cardiothoracic Surgery, Royal Children's Hospital, Melbourne, Australia.
    • J. Thorac. Cardiovasc. Surg. 2022 Jul 1; 164 (1): 186-196.e2.

    ObjectiveWe aimed to assess outcomes after aortic valve repair leading to bicuspid valve anatomy in children.MethodsThis is a retrospective study of patients who underwent aortic valve repair with creation/preservation of bicuspid aortic valve anatomy or tricuspidization of bicuspid valves between 1980 and 2016.ResultsOverall, 127 patients underwent bicuspid repair. Median age was 0.73 years (interquartile range, 0.1-8.9), and median weight was 8.15 kg (interquartile range, 3.9-31.7). The cohort included 22.8% neonates (n = 29), 28.3% infants (n = 36), and 48.8% children (n = 62). Repair was performed without a patch in 54.3% (n = 69). Survival at 10 years was 94.8% (95% confidence interval, 87.5-97.85). Freedom from aortic valve reoperation at 5 and 10 years was 79.9% (95% confidence interval, 71.2-86.2) and 65.6% (95% confidence interval, 53.4-75.3), respectively. Re-repair was undertaken in 53.7% (22/41). Freedom from aortic valve replacement at 5 and 10 years was 90.3% (95% confidence interval, 83.1-94.5) and 75.8% (95% confidence interval, 63-84.7), respectively. Risk factors for reoperation were age less than 1 year, unicuspid valve, and the presence of Shone complex and concomitant aortic arch repair. There were 107 patients (107/127, 84.25%) with preoperative bicuspid aortic valve morphology that was preserved. They were compared with a separate cohort of 44 patients who underwent tricuspidization of bicuspid aortic valve during the same period. There was no difference in survival or freedom from aortic valve reoperation. However, freedom from aortic valve replacement was lower after tricuspidization with 49.7% (95% confidence interval, 26.3-69.3) versus 75.8% (95% confidence interval, 62.1-85.1) after 10 years (P = .0118).ConclusionsAortic valve repair leading to bicuspid valve anatomy in children has satisfactory long-term results. Reoperation remains common, but the need for early valve replacement can be effectively delayed.Crown Copyright © 2022. Published by Elsevier Inc. All rights reserved.

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