• S. Afr. Med. J. · Aug 2021

    Hospital-based evaluation of tuberculosis-exposed neonates: An approach to complement the South African national guidance.

    • A Van der Westhuizen, A Dramowski, H S Schaaf, M Groenewald, and A Bekker.
    • Frere and Cecilia Makiwane hospitals, East London, South Africa. ananjavdw@gmail.com.
    • S. Afr. Med. J. 2021 Aug 2; 111 (8): 724-728.

    AbstractThe South African National Department of Health published updated guidelines in 2019 for the prevention of mother-to-child transmission of communicable diseases. The proposed management of a neonate born to a mother with tuberculosis (TB) was included, and recommended referral of all symptomatic TB-exposed neonates to hospital for TB evaluation. However, no standard approach exists for evaluating hospitalised, symptomatic TB-exposed neonates, including preterm and low-birthweight (LBW) neonates born to mothers with TB. We use a clinical case report to illustrate a suggested approach to hospital-based evaluation of TB-exposed neonates, including preterm and LBW neonates. Guidance for the interpretation of different TB screening investigations in this population is also provided.

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