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- Katia Micchia, Caterina Formica, Simona De Salvo, Nunzio Muscarà, Placido Bramanti, Fabrizia Caminiti, Silvia Marino, and Francesco Corallo.
- IRCCS Centro Neurolesi "Bonino-Pulejo", S.S. 113, Via Palermo, C. da Casazza, 98124 Messina, Italy.
- Medicine (Baltimore). 2022 Mar 4; 101 (9): e28922e28922.
AbstractIdiopathic normal pressure hydrocephalus (NPH) is a syndrome that affects elderly people and is characterized by excessive accumulation of cerebrospinal fluid in the brain ventricles. Diagnosis is based on the evaluation of clinical symptoms, which consists of a classic triad (Hakim triad), gait disturbances, cognitive impairment, and urinary incontinence. However, this complete triad is not always seen; therefore, it is difficult to make the diagnosis. NPH can be divided into primary or idiopathic NPH and secondary NPH. Diagnostic criteria for NPH remain a topic of discussion; however, the development of diagnostic techniques has brought new opportunities for diagnosis. The aim of this review is to present an overview of neurophysiological and neuropsychological approaches to support the clinical evaluation of patients with NPH and contribute to the differential diagnosis of NPH and dementia, as the clinical symptoms of NPH may resemble other neurodegenerative disorders.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
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