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- Andrew Gagel, Fawzi Zghyer, Christeen Samuel, and Seth S Martin.
- Johns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD 21287, USA.
- Med. Clin. North Am. 2022 Mar 1; 106 (2): 285-298.
AbstractOne's total atherosclerotic plaque burden is related to his or her cumulative exposure to low-density lipoprotein cholesterol (LDL-C) and other apoB-containing lipoproteins. Long-term exposure to lower LDL-C levels is associated with a lower risk of cardiovascular events compared with shorter term exposure to lower LDL-C. New lipid-reducing agents have been able to reduce LDL-C to previously unseen levels, showing efficacy in safely decreasing rates of atherosclerotic cardiovascular disease in primary and secondary prevention populations. To date, an LDL-C level less than which there is no clinical benefit has not yet been identified.Copyright © 2021 Elsevier Inc. All rights reserved.
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