• Med. Clin. North Am. · Mar 2022

    Review

    Drug Interactions: What Are Important Drug Interactions for the Most Commonly Used Medications in Preventive Cardiology?

    • Aziz Hammoud and Michael D Shapiro.
    • Section on Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
    • Med. Clin. North Am. 2022 Mar 1; 106 (2): 389-399.

    AbstractSignificant drug interactions contribute to hospitalizations, mortality, and health care costs. They often are preventable with a basic understanding of pharmacokinetics and pharmacodynamics. More than quarter of Americans above the age of 40 years take a statin, the most commonly used lipid-lowering therapy in modern times. Because of their pharmacokinetics, statins interact with numerous other drugs and substances, often in a manner that differs from statin to statin. This article provides an overview of important drug interactions for the most commonly used medications in preventive cardiology, with an emphasis on clinically significant interactions involving statins.Copyright © 2021 Elsevier Inc. All rights reserved.

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