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- H A Adams.
- Abteilung für Anaesthesie und Intensivmedizin, Marienkrankenhaus Trier-Ehrang.
- Anaesthesist. 1995 Dec 1; 44 Suppl 3: S573-9.
AbstractAIMS AND PATHOPHYSIOLOGY: Intensive care patients are exposed to a number of noxious stimuli. They require individual analgesia and sedation to reduce and moderate the stress response to endogenous and exogenous stressors. In patients with SIRS (systemic inflammatory response syndrome), pathophysiological conditions with multiple organ dysfunction or failure demand special efforts and a specific regimen of analgosedation. The main goals are the absence of cardiocirculatory depression or, if at all possible, cardiocirculatory stabilization, absence of negative pulmonary, renal, hepatic and immunological side effects, preservation of a moderate stress response, and vertical and horizontal control appropriate to the clinical situation.
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