• A&A practice · Mar 2022

    Case Reports

    Anesthetic Management of an Adult With Hyperekplexia Undergoing a Laparoscopic Colectomy: A Case Report.

    • Brian A Chang and Kyra R Bernstein.
    • From the Department of Anesthesiology, New York Presbyterian, Columbia University Irving Medical Center, New York, New York.
    • A A Pract. 2022 Mar 2; 16 (3): e01571.

    AbstractHyperekplexia is a rare genetic disorder characterized by an exaggerated startle response to innocuous stimuli. There are several case reports documenting the administration of general anesthesia to infants and children with hyperekplexia and 1 case report documenting the use of a labor epidural in a parturient. These cases suggest a possible resistance to depolarizing neuromuscular blocking agents and increased risk of malignant hyperthermia. There are no case reports of adults with hyperekplexia receiving general anesthesia. We report the case of a 20-year-old woman with hyperekplexia who safely received general anesthesia without neuromuscular blockade for a laparoscopic colectomy.Copyright © 2022 International Anesthesia Research Society.

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