• P Poullin and P Lefèvre.
• Service d'hémaphérèse et d'autotransfusion, hôpital de la Conception, 13385 Marseille cedex 05, France. pascale.poullin@ap-hm.fr
• Rev Med Interne. 2008 Apr 1; 29 (4): 290-6.

PurposeTherapeutic erythrocytapheresis is a selective red cell-depletion aphaeresis technique.Current Knowledge And Key PointUsing a discontinuous or continuous flow blood cell separator, the technique safely allows quickly and automatically collecting a large volume of red cells. The main obstacle of implementation is a poor peripheral venous access. The procedure is well-tolerated. Polycythemia vera, hereditary hemochromatosis, complicated sickle-cell-disease and retinal venous occlusion are the main clinical applications.Prospect And ProjectTherapeutic erythrocytapheresis is a more modern and more effective method than the classic patient-bleeding. It has to be preferred in the early treatment of patients with polycythemia vera and hereditary hemochromatosis.

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