• Presse Med · Oct 1999

    [Transmitted transfusion virus: a new hepatotropic virus...in search for a disease].

    • P Halfon and P Cacoub.
    • Laboratoire ALPHABIO, Marseille.
    • Presse Med. 1999 Oct 2; 28 (29): 1592-4.

    AbstractAN UBIQUITOUS VIRUS: The family of hepatitis viruses now has a new member discovered in 1997 by a Japanese team. The TTV (transmitted transfusion virus) is a small ubiquitous DNA virus probably largely distributed throughout the world. Prevalence in blood donors is about 2 to 10%. TRANSMISSION AND PERSISTENCE: TTV is generally transmitted via the parenteral route but can probably be transmitted via orofecal and matemo-fetal routes. The natural history of TTV has been studied in retrospective studies, particularly in hemophiliacs. After a post-transfusional peak, the virus appears to persist for long periods in the organism without causing liver damage nor any change in transaminase levels.

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