-
Review
[What possible treatments for liver cirrhosis patients with a small hepatocellular carcinoma?].
- J Belghiti and F Durand.
- Fédération Médico-Chirurgicale d'Hépato-Gastro-Entérologie, Hôpital Beaujon, Université Paris VII, Clichy. jacques.belghiti@bjn.ap-hop-paris.fr
- Presse Med. 2000 Apr 1; 29 (12): 681-8.
AbstractUNDERLYING LIVER DISEASE: Most cases of hepatocellular carcinoma (HCC) develop in subjects with an underlying chronic liver disease, primarily hepatitis C infection. The underlying liver disease greatly limits treatment possibilities due to the restrictions on surgery or the risk of recurrence even when surgical resection, chemoembolization or alcoholization appears to be successful. IN CASE OF NORMAL LIVER FUNCTION: Percutaneous destruction of the tumor with alcoholization or radiofrequency techniques can be effective against HCC tumors measuring less than 3 cm. Access is however sometimes limited, leading to partial destruction and risk of local recurrence. When the patient's liver functions are compatible with surgery, resection of the tumor and its adjacent portal segment has been found to be effective against tumors measuring 3 to 5 cm.
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