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  • Presse Med · Apr 2000

    Review

    [The renin-angiotensin system and progression of kidney disease].

    • F Alhenc-Gelas.
    • INSERM U367, Paris.
    • Presse Med. 2000 Apr 15; 29 (14): 806-10.

    AbstractCONSTRICTIVE ACTIVITY OF THE RAS AND DEVELOPMENT OF RENAL DISEASES: Several studies have suggested that the constitutive level of activity of the renin-angiotensin system (RAS), and especially of angiotensin converting enzyme (ACE) which plays an important role in the kidney in determining intrarenal angiotensin and kinin concentrations, is genetically determined and linked to the risk of developing several vascular diseases, including diabetic nephropathy, and to the risk of renal function deterioration in glomerular diseases of several origins.

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