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- B Vergès and J M Petit.
- Service Endocrinologie, Diabétologie et Maladies métaboliques, Hôpital du Bocage, F 21034 Dijon. bruno.verges@chu-dijon
- Presse Med. 2001 May 19; 30 (18): 911-4.
AbstractHYPERLIPIDEMIA: HIV-1 protease-inhibitors therapy is associated with increased levels of triglycerides, LDL-cholesterol and Lp(a). But the understanding of hyperlipidaemia occurring in patients treated with HIV-1 protease-inhibitors is not easy since HIV infection itself is associated with lipid abnormalities and since HIV-1 protease-inhibitors therapy is also responsible for the development of a lipodystrophy syndrome (insulin resistance) which may influence lipid metabolism. However, many data indicate that HIV-1 protease-inhibitors therapy itself modifies significantly lipid metabolism.
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