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- X Pourrat, J M Serekian, D Antier, and J Grassin.
- Service de Pharmacie, Centre Hospitalier Universitaire de Tours.
- Presse Med. 2001 Jun 9; 30 (20): 1031-6.
AbstractBASIC STRATEGY: Generalized tonic-clonic status epilepticus is a medical emergency requiring very rapid administration of anti-epilepsy drugs to avoid or prevent neurological damage. First intention treatment is based on rapid-action intravenous benzodiazepine (BZD) associated with another long-action anti-epilepsy drug. General anesthesia with respiratory assistance may be needed if the seizures are refractory. We considered the pharmacodynamic, pharmacokinetic and pharmacoeconomic properties of drugs proposed for the treatment of status epilepticus.
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