• Presse Med · Dec 2002

    Review

    [Efficacy of diacerein on the symptoms and radiographic progression of osteoarthritis].

    • D Provvedini and P Cohen.
    • Laboratoires Negma-Lerads, Toussus le Noble, France.
    • Presse Med. 2002 Dec 7; 31 (39 Pt 2): 4S13-5.

    SYMPTOMATIC EFFECTS OF DIACEREIN: Data obtained from several clinical trials have demonstrated that relief of joint pain obtained with the interleukin-1 inhibitor diacerein is comparable with that observed with non-steroidal anti-inflammatory drugs (NSAIDS) after four to six weeks of treatment and that relief persists after treatment withdrawal. Patients taking diacerein are less handicapped, use less NSAID and/or analgesics, and have lower demands for care as well as an improved quality of life. RADIOGRAPHIC FindingsThe ECHODIAH study conducted to evaluate the structure-modifying effect of diacerein in hip osteoarthritis.

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