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- Patrick Cherin.
- Service de médecine interne I, Hôpital Salpétrière, Paris. patrick.cherin@psl.ap-hop-paris.fr
- Presse Med. 2003 Oct 25; 32 (35): 1668-75.
AbstractTHE TREATMENT OF DM AND PM: Among primary inflammatory muscle diseases, there are three principle subsets depending on immuno-histochemical and clinical aspects: dermatomyositis (DM), polymyositis (PM) and inclusion body myositis (IBM). Despite their physiopathogenic differences, the treatment of PM and DM is very similar. It relies on principally on oral corticosteroid therapy, occasionally initiated via the intravenous route and which is active in 50 to 70% of cases. In patient with primary or secondary resistance, intolerance or dependence regarding corticosteroids, a second treatment line with immunosuppressive agents or intravenous immunoglobulin should be added.
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