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- T Nagel, J R Kalden, and B Manger.
- Medizinische Klinik III und Institut für Klinische Immunologie, Friedrich-Alexander-Universität Erlangen-Nürnberg.
- Med Klin. 1998 Oct 15; 93 (10): 592-7.
AbstractT CELL RESPONSE: T lymphocytes play a key role in the coordination of the immune response. T helper cells contribute primarily by means of cytokine release, whereas cytotoxic T cells eliminate cells bearing antigens recognized as foreign. Through its T cell receptor each T cell can recognize a specific peptide antigen, which is presented in the context of the major histocompatibility complex (MHC) to T helper cells by specialized antigen-presenting cells or to cytotoxic T cells by nearly all body cells. Upon contact with its specific antigen, the T cell receptor transduces an activation signal into the T cell, leading to proliferation, cytokine production, or efficient cytotoxicity.
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