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- Tammi Schaeffer.
- Rocky Mountain Poison and Drug Center-Denver Health, Denver, CO, USA. Tammi.Schaeffer@rmpdc.org
- J Med Toxicol. 2012 Dec 1;8(4):400-7.
AbstractThe increased use of opioid pain medication has been mirrored by the increased misuse and abuse of these drugs. As part of a multidisciplinary approach to this epidemic, pharmaceutical companies, with the encouragement of the Food and Drug Administration, have increased the development of abuse-deterrent formulations. While all have the goal of treating pain while mitigating misuse and abuse, there are different technologies utilized to impart the abuse-deterrent properties. The goal of this paper is to review the basis of abuse-deterrent formulations, the different types and approaches of some of the abuse-deterrent products, and their current regulatory status in the USA.
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