• Chang Hoon Ahn and Soon Chul Kim.
• Department of Pediatrics, Chonbuk National University Medical School and Hospital, Research Institute of Clinical Medicine of Chonbuk National University - Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
• Medicine (Baltimore). 2017 Nov 1; 96 (46): e8074.

RationaleColorectal cancer in children is rare, with delayed diagnosis and advanced stage at presentation in high mortality. Early detection of colorectal cancer is, therefore, important for better prognosis.Patient ConcernsThirteen-year-old boy presented with symptoms of melena, vomiting, and abdominal pain for 6 months. 18-year-old girl was hospitalized due to the symptoms of hematochezia, and persistent abdominal pain for 6 months. They have no chronic disease or familial history of malignancy.DiagnosesWe encountered 2 teenagers diagnosed with colorectal cancer.InterventionsBoth patients had the same histological findings in postoperation colonic biopsy and underwent surgical resection.OutcomesThe boy fully recovered with only surgery, but the girl died, despite receiving adjuvant chemotherapy for the advanced stage of cancer.LessonsWe recommend early and active evaluation, including a pediatric colonoscopy, in a child with suspected malignancy.

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