• Qi Lai, Conglin Ye, Tian Gao, Jun Xiao, An Xie, Xuqiang Liu, Xiaolong Yu, Jun Liu, Min Dai, Hucheng Liu, and Bin Zhang.
• Department of Orthopedics, Multidisciplinary Therapy Center of Musculoskeletal Tumor and Artificial Joints Engineering Technology Research Center of Jiangxi Province, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
• Medicine (Baltimore). 2017 Nov 1; 96 (46): e8672.

RationaleOsteosarcoma is the most common malignant bone tumor in children and adolescents. Metastasis occurs early, the mortality rate is high, and the tumor results in a tremendous physical, mental, and economic burden on patients. Therefore, the treatment of osteosarcoma has been important for orthopedic surgeons. However, treatment has always been a difficult problem globally.Patient ConcernWe present the case of a 22-year-old girl with increasing local pain in the distal left thigh.DiagnosesThe patient was initially diagnosed as bone cancer according to computed tomography (CT) and X-ray imaging. And the patient was further diagnosed as osteosarcoma via to puncture biopsy of the left distal femur.InterventionsLocal arterial infusion chemotherapy, systemic intravenous chemotherapy, and curettage was conducted because of limb salvage program.OutcomesThe patient was doing well with no evidence of local or distant recurrence 7 years after the surgery.LessonsOur case indicated that limb osteosarcoma patients can undergo a limb salvage program of local arterial infusion chemotherapy, systemic intravenous chemotherapy, and curettage.

18 keywords...

hide…