• Yubo Wang, Jiayue Cui, Xu Yan, Rihua Jin, and Xinyu Hong.
• aDepartment of Neurosurgery, First Hospital of Jilin University bDepartment of Histology and Embryology, College of Basic Medical Sciences, Jilin University cDepartment of Pathology, First Hospital of Jilin University, Changchun, Jilin, P.R. China.
• Medicine (Baltimore). 2017 Nov 1; 96 (46): e8790.

RationalAlveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity.Patient ConcernsWe report our experience with a 19-year-old pregnant woman who presented with intermittent headaches and vomiting at 38 weeks gestation.DiagnosesThe patient was initially diagnosed as brain metastasis according to computed tomography and magnetic resonance imaging (MRI) imaging.InterventionsCesarean section and craniotomy (complete resection of both brain metastatic lesions) was performed sequentially.OutcomesA healthy baby girl was delivered safely and no neonatal malformations were found. Histological analysis confirmed the diagnosis of ASPS. Follow-up MRI performed 10 months after surgery revealed no residual tumor or signs of recurrence.LessonsWe report a case of ASPS with multiple brain and lung metastases in a pregnant woman. We recommend timely MRI examination for diagnosis and have discussed the approach to the treatment of pregnant women with brain metastasis.

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