• Yiming Chu, Qingqu Guo, and Dan Wu.
• Department of Surgery, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, P.R. China.
• Medicine (Baltimore). 2017 Dec 1; 96 (48): e8792.

RationaleGastrointestinal stromal tumor and mesenteric fibromatosis are rare mesenchymal tumors. Coexistence of these two diseases is uncommon, with only a few anecdotal reports of individuals.Patient ConcernsClinical data and treatment of a 43-year-old man with subsequent mesenteric fibromatosis from gastrointestinal stromal tumor are summarized. The Ethics Committee of The Second Affiliated Hospital, College of Medicine, Zhejiang University approved this study, and the patient provided written informed consent form.DiagnosesThe initial diagnosis of the recurrent mesenteric mass was recurrent gastrointestinal stromal tumor.InterventionsThe operation was performed as possible at the time when the mass was found after the first surgery.OutcomesThe diagnosis was revised as mesenteric fibromatosis according to the postoperative immunohistochemical staining. The postoperative condition was normal without adjuvant therapy and no recidivation has been found.LessonsThe potential for the coexistence of gastrointestinal stromal tumor and mesenteric fibromatosis should always be considered.

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