• Medicine · Jan 2018

    Case Reports

    Daily 10 mg rivaroxaban as a therapy for ventricular thrombus related to left ventricular non-compaction cardiomyopathy: A case report.

    • Huan Sun, Qini Zhao, Yanjing Wang, Robert Lakin, Haiyan Feng, Xingyu Fan, Huiling Luo, Dongmei Gao, Lin Liu, Yuquan He, and Ping Yang.
    • Cardiology Department.
    • Medicine (Baltimore). 2018 Jan 1; 97 (4): e9670.

    RationaleLeft ventricular non-compaction cardiomyopathy (LVNC) is a rare heart disorder related to thrombosis. Anticoagulant therapy is suggested for the treatment of this disease. The success of the novel oral anticoagulant rivaroxaban as a treatment option for this disorder is unclear.Patient ConcernsA 43-year-old man who felt dizzy at rest was found to have an intraventricular thrombus.DiagnosesThe thrombus was confirmed by echocardiography. And LVNC was diagnosed by cardiac magnetic resonance (CMR) and echocardiography.InterventionsHe was prescribed a low dose (10 mg daily) of rivaroxaban as treatment.OutcomesAfter 3 months, the thrombus diminished, and the manifestation disappeared.LessonsLow dose of rivaroxaban may serve as a viable option for anticoagulation therapy in LVNC patients, with large clinical trials needed to determine the best course of treatment.

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