• Rong Niu, Jian-Feng Wang, Da-Chuan Zhang, Xiao-Liang Shao, Chun Qiu, and Yue-Tao Wang.
• Department of Nuclear Medicine.
• Medicine (Baltimore). 2018 Jan 1; 97 (4): e9720.

RationaleLow-grade myofibroblastic sarcoma (LGMS) is a rare mesenchyme-derived tumor, which usually occurs in head, neck (especially tongue and mouth), and limbs. In this report, we described a case of gastric LGMS by F-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography/computed tomography (PET/CT), which has not been reported previously.Patient ConcernsA 51-year-old female patient was admitted to our hospital with upper abdominal discomfort for 1 year and gradually increased eating difficulties over the last 3 months. From gastroscopy, an ulcer of 1.0 cm × 1.2 cm at the entrance of cardia and stiffness of peripheral mucosa were found, leading to suspicion of cardia cancer. F-FDG PET/CT was performed for further diagnosis and staging.DiagnosesAccording to pathological findings in combination with immunohistochemical features, diagnosis of gastric LGMS was made.InterventionsTo relieve symptoms of upper gastrointestinal obstruction in the patient, proximal gastrectomy was carried out 1 week after the F-FDG PET/CT scan.OutcomesThe patient died due to advanced tumor.LessonsF-FDG PET/CT scan showed local thickening of the gastric wall, invasion of adjacent soft tissue, diaphragmatic and peritoneal metastasis at early stage, absence of regional lymph node metastasis, and increased F-FDG metabolism in primary tumor and metastatic tumor.

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