• Xiaoreng Feng, Sheng Zhang, Hongfeng Liang, Bin Chen, and Frankie Leung.
• Department of Orthopaedics and Traumatology, Yangjiang People's Hospital, Yangjiang, 529500, China; Division of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
• Injury. 2022 Jul 1; 53 (7): 2533-2540.

BackgroundLocking screws with a typical buttress thread have high levels of failure in patients with osteoporotic bones. This study aims to develop a novel thread design for the locking screw and compare its fixation stability with the typical buttress thread.MethodsLocking screws with a novel thread design that possess an undercut feature and locking screws with a typical buttress thread were manufactured from stainless steel. Their fixation stabilities were then evaluated individually under a lateral migration test and evaluated in pairs together with a locking plate (LP) in an osteoporotic bone substitute under cyclic craniocaudal and torsional loadings. A finite element analysis (FEA) model was constructed to analyze the stress distributions present in the bone tissue adjacent to the novel thread versus the buttress thread.ResultsThe biomechanical test revealed that the novel thread had a significantly higher lateral migration strength than the buttress thread. When applied to a LP, the locking screw with the novel thread requires more cycles and higher forces or torque to resist migration up to 5 mm or 10° than the buttress thread. The FEA simulation showed that the novel thread can make the stress distribute more evenly at the adjacent bone tissue when compared with the buttress thread.ConclusionsThe locking screw with the novel undercut thread had superior lateral migration resistance during both initial and continued migration and superior fixation stability when applied to a LP under both cyclic craniocaudal loading and torsional loading than the locking screw with a typical buttress thread.Copyright © 2022. Published by Elsevier Ltd.

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