• Neurosurgery · Apr 2022

    Cost-Effectiveness Analysis of Encephaloduroarteriosynangiosis Surgery for Symptomatic Intracranial Atherosclerotic Disease.

    • Nestor R Gonzalez, Miguel D Quintero-Consuegra, Julie L Chan, Daniel Chang, Chi-Hong Tseng, and Jeffrey L Saver.
    • Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
    • Neurosurgery. 2022 Apr 1; 90 (4): 495500495-500.

    AbstractEncephaloduroarteriosynangiosis (EDAS) is a promising treatment for cerebral arterial steno-occlusive disorders, with proven efficacy in moyamoya disease and a growing interest in potential application for patients with symptomatic intracranial atherosclerotic disease, given the early results of intermediate development trials showing reduced rates of recurrence stroke and improved clinical outcomes compared with those patients treated with intense medical management (IMM) alone. Although clinical outcomes are the fundamental goal when considering patient care paradigms, a cost-effective analysis is key to obtaining a comprehensive understanding of the impact EDAS may provide to patients with atherosclerotic disease on a larger scale. Here, we evaluate the EDAS + IMM cost-effectiveness over time in the treatment of intracranial atherosclerotic disease compared with IMM alone.Copyright © Congress of Neurological Surgeons 2022. All rights reserved.

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