• Julie C Lauffenburger, William H Shrank, Asaf Bitton, Jessica M Franklin, Robert J Glynn, Alexis A Krumme, Olga S Matlin, Edmund J Pezalla, Claire M Spettell, Gregory Brill, and Niteesh K Choudhry.
• From Brigham and Women's Hospital, Ariadne Labs, Harvard T.H. Chan School of Public Health, and Harvard Medical School, Boston, Massachusetts; CVS Health, Woonsocket, Rhode Island; and Aetna, Hartford, Connecticut.
• Ann. Intern. Med. 2017 Jan 17; 166 (2): 81-88.

BackgroundDespite the widespread adoption of patient-centered medical homes into primary care practice, the evidence supporting their effect on health care outcomes has come primarily from geographically localized and well-integrated health systems.ObjectiveTo assess the association between medication adherence and medical homes in a national patient and provider population, given the strong ties between adherence to chronic disease medications and health care quality and spending.DesignRetrospective cohort study.SettingClaims from a large national health insurer.PatientsPatients initiating therapy with common medications for chronic diseases (diabetes, hypertension, and hyperlipidemia) between 2011 and 2013.MeasurementsMedication adherence in the 12 months after treatment initiation was compared among patients cared for by providers practicing in National Committee for Quality Assurance-recognized patient-centered medical homes and propensity score-matched control practices in the same Primary Care Service Areas. Linear mixed models were used to examine the association between medical homes and adherence.ResultsOf 313 765 patients meeting study criteria, 18 611 (5.9%) received care in patient-centered medical homes. Mean rates of adherence were 64% among medical home patients and 59% among control patients. Among 4660 matched control and medical home practices, medication adherence was significantly higher in medical homes (2.2% [95% CI, 1.5% to 2.9%]). The association between medical homes and better adherence did not differ significantly by disease state (diabetes, 3.0% [CI, 1.5% to 4.6%]; hypertension, 3.2% [CI, 2.2% to 4.2%]; hyperlipidemia, 1.5% [CI, 0.6% to 2.5%]).LimitationClinical outcomes related to medication adherence were not assessed.ConclusionReceipt of care in a patient-centered medical home is associated with better adherence, a vital measure of health care quality, among patients initiating treatment with medications for common high-cost chronic diseases.Primary Funding SourceCVS Health.

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