• Am. J. Med. · Jun 2022

    Review

    Psychological Stress and Heart Disease: Fact or Folklore?

    • Glenn N Levine.
    • Baylor College of Medicine, Houston, Texas; Cardiology Section, Michael E. DeBakey VA Medical Center, Houston, Texas. Electronic address: glevine@bcm.tmc.edu.
    • Am. J. Med. 2022 Jun 1; 135 (6): 688-696.

    AbstractFor at least a few centuries, if not millennia, psychological stress has been popularly believed to contribute to heart disease. Does psychological stress really contribute to heart disease? Are anecdotal, patient, and lay press reports that angina, heart attack, and even cardiac death are caused by stress based on fact, or are they just folklore? In this review, the study data supporting associations between stress and cardiovascular risk, as well as potential mechanisms by which psychological stress might contribute to heart disease and precipitate myocardial ischemia and infarction, are critically reviewed and summarized.Published by Elsevier Inc.

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