• Kang Chen, Ping Li, Yi-Jun Li, Ting Li, and Yi-Ming Mu.
• a Department of Endocrinology , Chinese PLA General Hospital , Beijing , China.
• Postgrad Med. 2016 Nov 1; 128 (8): 783-789.

ObjectiveTo investigate the association between hypertriglyceridemic waist (HTGW) phenotype and arterial stiffness in a Chinese population without hypertension, diabetes and cardiovascular diseases.MethodsA total number of 3028 subjects aged 40 years and over were enrolled in this cross-sectional study. All participants provided a clinical history and underwent a physical examination. Brachial-ankle pulse wave velocity (baPWV) was used to evaluate arterial stiffness. HTGW phenotype was defined as the simultaneous presence of waist circumference ≥90/80 cm and triglycerides ≥2.0/1.5 mmol/L in men/women.ResultsThe prevalence of HTGW phenotype was 7.5% among healthy participants in China (Beijing), 7.4% in men and 7.5% in women. Women with HTGW phenotype had a higher level of baPWV compared with normal WC and normal triglyceride (NWNT) group (P < 0.05), but no significant difference was observed in men (P > 0.05). Multiple logistic regression analysis showed HTGW phenotype was significantly associated with baPWV after controlling for multiple factors in women. However, no significant relationship was observed in men.ConclusionsThe present study supports that HTGW phenotype is associated with increased arterial stiffness in women but not in men.

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