• Ji Tu, Wentian Li, Shenglei Shu, Yukun Zhang, Wenbin Hua, Shuai Li, Shuhua Yang, and Cao Yang.
• Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Wuhan Institute of Biological Products Co., Ltd., Wuhan, Hubei, People's Republic of China Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan. China.
• Medicine (Baltimore). 2018 May 1; 97 (20): e10799.

RationaleSpinal Giant Cell Tumors (SGCTs) are rare, aggressive, and benign tumors. Their presence in the cervical spine is even more exceptional. There are few reports of cervical GCT in the literature, especially recurrent cases. The treatment are challenging to clinically because radical resection is extremely difficult.Patient ConcernsIn this study, we present the cases of a 25-year-old man and a 41-year-old woman who suffered from recurrent cervical GCT.InterventionsThey underwent extensive total spondylectomy of C3-5 and C2-4, respectively, by a combined anterior and posterior approach.OutcomesBoth patients had a satisfactory prognosis after 2 years followe-up, and extensive total spondylectomy provided good disease-free survival rates. Extensive total spondylectomy of cervical recurrent giant cell tumor was successfully achieved combined anterior and posterior approach.LessonsThis surgical technique can be an effective option for this pathological condition, which is difficult to manage using other conventional treatment options including repeated curettage and radiotherapy. However, there are insufficient data on long-term subjective outcomes in this type of patient, and larger series studies are needed to determine the efficacy of this approach, especially compared with piecemeal resection techniques.

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